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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Feb 17;31(5):1116–1123. doi: 10.1161/ATVBAHA.110.214601

Figure 2.

Figure 2

CyPA deficiency reduces AngII-induced perivascular cell number and fibrosis. (A) Representative H&E staining of hearts from Apoe−/− and Apoe−/− Ppia−/− mice infused with saline or AngII for 4 weeks. (B) Representative H&E and Elastica Masson (E&M) staining of coronary arteries from Apoe−/− and Apoe−/− Ppia−/− mice infused with AngII for 4 weeks. Elastic fibers stain black and collagen fibers stain red. (C) Statistical analysis of the number of cells in the perivascular area in Apoe−/− (n = 9) and Apoe−/− Ppia−/− (n = 7) mice. (D) Statistical analysis of the perivascular fibrotic area per total vascular area in Apoe−/− (n = 9) and Apoe−/− Ppia−/− (n = 7) mice. Results are mean ± SD. # equals P< 0.05 in Saline versus AngII; *equals P< 0.05 in Apoe−/− versus Apoe−/− Ppia−/− mice.