Table 3.
Strategic or non-strategic localization of MRI lesions and cognitive impairment.
| MRI marker | n | MDRS score (se) | p-Value‡ |
|---|---|---|---|
| White matter hyperintensitiesa | |||
| None | 0 | ||
| Non-strategic | 0 | NA | |
| Strategic | 134 | 131.6 (1.8) | |
| Lacunar lesionsa | |||
| None | 11 | 135.9 (5.5) | 0.70 |
| Non-strategic | 14 | 134.7 (5.0) | |
| Strategic | 107 | 131.8 (1.8) | |
| Cerebral microhemorrhages | |||
| None | 91 | 134.3 (2.0) | 0.04 |
| Non-strategic | 18 | 131.4 (4.5) | |
| Strategic | 29 | 123.5 (3.7) | |
Strategic and non-strategic location of lesions were determined as outlined in the Section 2 (see text for details); se, standard error; NA, not applicable.
a
WMH was not available in 4 patients and lacunar lesions were not available in 6 patients.
‡
Adjusted for age and sex.