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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Biochem Pharmacol. 2001 Sep 1;62(5):569–580. doi: 10.1016/s0006-2952(01)00695-5

Fig. 1.

Fig. 1

Antileishmanial activity of ASM against axenic amastigotes and promastigotes of L. amazonensis, L. donovani, and L. major. Growing cultures of the cells (~5 × 106 cells/mL) were incubated with 20 µM SSM (control) or ASM for 20 hr at 25°, pH 7.5 (promastigotes) or at 35°, pH 4.5 (axenic amastigotes). SSM had less than a 2% effect on the growth of the cells at this concentration. Results are means ± SEM (N = 6). The differences of the antisense activities of ASM between the promastigotes and the amastigotes for each species were statistically significant (P < 0.01).