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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Pediatr Res. 2011 Apr;69(4):285–292. doi: 10.1203/PDR.0b013e31820bd165

Figure 5. Neonatal stress and morphine treatment effects on cellular metabolism gene sets.

Figure 5

Composite heat maps from severely stressed animals compared to severely stressed animals treated with morphine. Highlighted are gene sets related to energy metabolism. While there is some variability from animal to animal (columns), and by individual gene (rows), the treatment of stress with morphine clearly increased gene expression in many of the genes in each family relating to aerobic respiration, cellular response to stress, and ATP synthesis coupled electron transport (GSA p-value < 0.0001). Since the number of genes in the gene sets precludes adequate visibility, supplementary table S5 (http://links.lww.com/PDR/XXX) is provided listing the gene names in the same order as they appear in the heatmaps (top to bottom).