Table 1. Baseline Characteristics of the Study Cohort in 1990.
| Aspirin Tablets (325 mg) per week † | |||||
|---|---|---|---|---|---|
| Characteristics | None (n=18570) |
0.5-1.5 (n=36923) |
2-5 (n=16392) |
6-14 (n=11666) |
>14 (n=4129) |
| Age, mean (SD), y | 56.5 (7.3) | 55.9 (7.1) | 56.8 (7.1) | 57.8 (7.0) | 58.8 (6.9) |
| Body mass index, mean (SD), kg/m2‡ | 25.0 (6.3) | 24.9 (6.1) | 25.4 (6.2) | 25.6 (6.5) | 26.3 (6.9) |
| Current NSAID use, No. (%)§ | 1957 (10.5) | 4796 (13.0) | 3309 (20.2) | 3085 (26.4) | 1364 (33.0) |
| Physical activity, mean (SD), mets/wk | 15.3 (20.7) | 15.7 (22.5) | 15.5 (22.5) | 15.2 (20.6) | 14.1 (18.8) |
| Diabetes mellitus, No. (%) | 993 (5.4) | 1471 (4.0) | 844 (5.2) | 771 (6.6) | 284 (6.9) |
| Hypercholesterolemia, No. (%) | 6169 (33.2) | 12744 (34.5) | 6416 (39.1) | 4899 (42.0) | 1759 (42.6) |
| Hypertension, No. (%) | 5086 (27.4) | 9665 (26.2) | 5490 (33.5) | 4560 (39.1) | 1866 (45.2) |
| Coronary artery disease, No. (%) | 238 (1.3) | 380 (1.0) | 447 (2.7) | 363 (3.1) | 113 (2.7) |
| Osteoarthritis, No. (%) | 4615 (24.9) | 9982 (27.0) | 6123 (37.4) | 5907 (50.6) | 2750 (66.6) |
| Smoking status | |||||
| Past, No. (%) | 6750 (36.4) | 13817 (37.4) | 6529 (39.8) | 4729 (40.5) | 1571 (38.1) |
| Current, No. (%) | 3682 (19.8) | 6171 (16.7) | 2813 (17.2) | 1969 (16.9) | 780 (18.9) |
| Mean alcohol use, mean (SD), g/day | 4.94 (9.6) | 5.10 (9.4) | 5.51 (9.7) | 5.75 (10.4) | 5.47 (10.4) |
†
One standard table is 325 mg of aspirin.
‡
Body mass index is weight in kilograms divided by the square of the height in meters.
§
Current NSAID use is defined as regular intake of at least 2 tablets per week.