Table 2.
Summary of genotype and association results for the two SNPs mapping to the IL-13 gene vicinity for PsV and UK controls samples
| SNP | Genotype | Controls (n = 5199) | PsV cases (n = 743) | |||||
|---|---|---|---|---|---|---|---|---|
| Count/Frq | RAF | HWE | Count/Frq | RAF | ptrend | OR (CI) | ||
| rs1800925 | CC | 3480 (66.9) | 511 (68.8) | 1.07 (0.92 to 1.24) | ||||
| CT | 1531 (29.4) | 0.82 | 0.96 | 211 (28.4) | 0.83 | 0.34 | ||
| TT | 169 (3.3) | 21 (2.8) | ||||||
| rs20541 | GG | 3506 (67.4) | 498 (67.0) | 0.97 (0.85 to 1.12) | ||||
| GA | 1521 (29.3) | 0.82 | 0.85 | 217 (29.2) | 0.82 | 0.72 | ||
| AA | 168 (3.2) | 27 (3.6) | ||||||
Genotype counts are presented with frequencies in parentheses.
HWE, Hardy–Weinberg equilibrium (reported in controls only); n, number; RAF, risk allele frequency.