Table I. AP-MS data with ≥0.5 AvgP SAINT value.

Indicated baits and prey (HUGO gene names) with AvgP. Spectral indicates the spectral counts in each of the biological replicates. AvgP is the average of the individual probabilities. Control indicates the number of spectral counts in control runs (See Supplemental Table I for unfiltered data).

Bait	Prey	Spectral	Control	AvgP
PPP5C_WT	STIP1	84|44|30|26	0|0|0|0|0	1
PPP5C_WT	PPP5C	48|96|45|44	0|0|0|0|0	1
PPP5C_WT	HSPA8	33|40|19|47	26|26|20|20|18	0.94
PPP5C_WT	HSPA1B	59|50|42|81	36|25|24|18|17	0.9
PPP5C_WT	HSP90AB1	61|53|33|76	9|8|7|4|4	0.84
PPP5C_WT	HSP90AA1	61|41|31|54	10|9|7|7|4	0.69
PPP5C_WT	CCT4	0|4|2|1	0|0|0|0|0	0.67
PPP5C_WT	CDC37	5|3|0|0	0|0|0|0|0	0.5
PPP5C_MUT	PPP5C	108|42|42|22	0|0|0|0|0	1
HSP90AA1	STIP1	49|96|81|77	0|0|0|0|0	1
HSP90AA1	HSP90AB1	2265|1771|1406|716	9|8|7|4|4	1
HSP90AA1	HSP90AA1	2608|2222|1676|853	10|9|7|7|4	1
HSP90AA1	HSPA1B	292|240|177|122	36|25|24|18|17	1
HSP90AA1	HSPA8	189|224|197|124	26|26|20|20|18	1
HSP90AA1	CDC37	41|23|11|29	0|0|0|0|0	1
HSP90AA1	FKBP4	16|21|8|38	0|0|0|0|0	0.99
HSP90AA1	STUB1	20|28|9|14	0|0|0|0|0	0.99
HSP90AA1	TOMM34	2|4|3|6	0|0|0|0|0	0.99
HSP90AA1	FKBP5	3|7|24|5	0|0|0|0|0	0.99
HSP90AA1	GIGYF2	2|2|2|4	0|0|0|0|0	0.97
HSP90AA1	FKBP8	3|6|10|1	0|0|0|0|0	0.95
HSP90AA1	TUBB2B	167|118|215|73	37|31|29|0|0	0.94
HSP90AA1	SSBP1	4|8|6|10	1|0|0|0|0	0.94
HSP90AA1	TUBB	207|167|301|88	66|49|40|40|38	0.93
HSP90AA1	TUBA1A	287|190|190|80	23|27|45|33|0	0.93
HSP90AA1	TUBB2C	173|130|302|86	57|43|42|40|37	0.87
HSP90AA1	DNAJA1	2|4|12|1	2|1|0|0|0	0.66
HSP90AA1	RPAP3	1|0|4|3	0|0|0|0|0	0.66
HSP90AA1	PDRG1	1|3|3|0	0|0|0|0|0	0.64
HSP90AA1	DNAJA2	2|4|4|3	2|1|1|0|0	0.63
HSP90AA1	FASN	2|2|1|0	0|0|0|0|0	0.63
HSP90AA1	TTC4	1|1|0|3	0|0|0|0|0	0.61
HSP90AA1	HSPA4	0|1|1|5	0|0|0|0|0	0.6
HSP90AA1	POLR2E	2|1|2|3	2|0|0|0|0	0.57
HSP90AA1	IRS4	0|1|9|8	1|0|0|0|0	0.54
HSP90AA1	TUBAL3	9|7|4|9	3|0|0|0|0	0.52