Table 2.

Donor/recipient HLAalleles

Patient/donor	HLA class I alleles						HLA class II alleles				Allele level MM
	A1	A2	B1	B2	Cw1	Cw2	DRB1-1	DRB1-2	DQB1-1	DQB1-2	GVH	HVG
Patient 1	201	201	702	2705	0401/09N	102	401	701	304	303	4	5
Donor—father	201	3101	1302	4001	0401/09N	304	401	404	304	302
Patient 2	3001	3201	1302	3801	602	1203	901	1301	0303/12	603	5	5
Donor—brother	3001	2402	1302	3503	602	0401/09N	901	1501	0303/12	0602/19
Patient 3	301	6802	702	0705/06	702	1505	1501	1102	0602/19	0301/09	5	5
Donor—mother	301	3001	702	4201	702	1701/02/03	1501	302	0602/19	402

HLA alleles were defined through a combination of sequence-based typing and reverse sequence-specific oligonucleotide hybridization. Mismatched alleles on the unshared donor haplotype are indicated in the shaded boxes. All donors are fully mismatched in the direction of rejection (Host vs graft) at all HLA loci tested. Because patient 1 is homozygous at the HLA-A locus, there are only four allele mismatched in the graft vs host vector.