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. Author manuscript; available in PMC: 2012 May 15.
Published in final edited form as: Am J Med Genet C Semin Med Genet. 2011 Apr 15;157(2):83–89. doi: 10.1002/ajmg.c.30300

Figure 1. Cumulative incidence and annual hazard rates and by age.

Figure 1

(a, b) Cumulative incidence for cancer and cancer-free death by age in patients with Noonan syndrome (a) and Costello syndrome (b) and 95% CIs (shaded regions). (c, d) Annual hazard rates (incidence rate per year among subjects who are still susceptible) of cancer-free death or cancer, and 95% point-wise confidence envelopes (shaded regions) for Noonan syndrome (c) and Costello syndrome (d).