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. 2010 Jun;16(6):926–935. doi: 10.3201/eid1606.091623

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Phylogenetic analysis of influenza A (H1N1) neuraminidase genes (A) and geographic distribution of oseltamivir-resistant viruses (ORVs) (B) isolated from Tottori Prefecture, Japan, 2007–08. ORVs fell into either Northern-Eu lineage (red) or Hawaii lineage (blue); Tottori ORVs and current vaccine strains are indicated by black and purple, respectively. A) ORVs formed 3 subclades: T-1, sharing V75A and D354G; T-2, without common changes; and T-3, sharing M188L. Sampling dates are given after each strain name. Scale bar indicates nucleotide substitutions per site. B) Tottori Prefecture is geographically divided into 3 areas, comprising 19 cities. ORVs from Tottori were collected from 4 cities over 2 areas. The sampling month for each ORV is indicated by a triangle (January), circle (February), or square (March). *Zanamivir resistant.