Table 2.
CYP2J2*7 association with different disease risks
| Disease | Population | Study size | Association | References |
|---|---|---|---|---|
| CAD | German | 289 patients with CAD 255 controls |
Yes – increased risk | [2] |
| CAD | German | 2547 patients with CAD 696 controls |
No | [29] |
| CHD | African–American | 200 CHD cases 260 non-CHD cases |
Yes – lower risk | [32] |
| CHD | Caucasian | 692 CHD cases 493 non-CHD cases |
No | [32] |
| MI | German | 1350 CAD patients with MI 1197 CAD patients without MI 696 controls |
No | [29] |
| MI | Han Chinese | 200 patients 200 controls |
Yes – increased frequency | [28] |
| MI | German | 1000 individuals | No | [33] |
| Acute coronary syndromes; brain ischemia | German | 289 patients with CAD 255 controls |
No | [2] |
| Cerebrovascular accident risk | Chinese | 200 patients with ischemic stroke 350 controls |
No | [26] |
| Ischemic coronary events; cerebrovascular events | Swedish | 5740 participants | No | [34] |
| Hypertension | African–American | 108 patients with hypertension 107 normotensive controls |
No | [24] |
| Hypertension | African–American | 76 hypertensive patients 73 normotensive participants |
No | [23] |
| Hypertension | Caucasian | 123 hypertensive patients 116 normotensive participants |
Yes – decreased risk in male patients | [23] |
| Hypertension | Russian | 295 patients with hypertension 281 healthy controls |
Yes – increased risk | [30] |
| Asthma | Russian | 215 patients with asthma 214 healthy controls |
Yes – increased susceptibility | [35] |
| Calcineurin inhibitor induced nephrotoxicity | Caucasian | 163 participants | No | [36] |
CAD, coronary artery disease; CHD, coronary heart disease; MI, myocardial infarction.