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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Mar 2;252(3):259–267. doi: 10.1016/j.taap.2011.02.017

Figure 2.

Figure 2

Nonylphenol activates mouse PXR. Western blots of Cyp2b, Cyp3a, and β-actin from hepatic microsomes of untreated, 50 or 75 mg/kg/day nonylphenol treated as described in the Materials and Methods. Actin was used as a housekeeping gene. A) Wild-type male and female untreated and NP-treated mice. B) PXR-null male and female untreated and NP-treated mice. Blots were quantified densitometrically and the relative mean differential expression as compared to the controls is reported above the blots. An asterisk indicates a statistically significant difference compared to the untreated group using Student's t-test (p < 0.05).