Table 1. Comparison of CYP expression between WT and PXR-null mice.

CYP	WT Female	PXR-null Female	WT Male	PXR-null Male
Cyp2b9	14.97 ± 4.96 a**	6.47 ± 1.27	1.00 ± 0.81	0.69 ± 0.46
Cyp2b10	2.42 ± 0.53	23.64 ± 5.53 b**	1.00 ± 0.41	6.74 ± 2.28 d**
Cyp2c29	0.82 ± 0.28	1.42 ± 0.85	1.00 ± 0.28	1.87 ± 0.44
Cyp3a11	1.19 ± 0.24	0.31 ± 0.06 b*	1.00 ± 0.24	0.26 ± 0.08c*
Cyp3a41	60.98 ± 15.31 a*	125.37 ± 23.26 b*	1.00 ± 0.76	0.85 ± 0.31d**

Data is expressed as relative data ± SEM

^*P-value < 0.05 and

^**p-value < 0.01; indicate statistical significance by one-way ANOVA followed by Dunnett's multiple comparison test.

^aIndicates significant difference between WT female and WT male.

^bIndicates significant difference between WT female and PXR-null female mice.

^cIndicates significant difference between WT male and PXR-null male mice.

^dIndicates significant difference between PXR-null female and PXR-null male mice.