Table 2. Comparison of CYP expression between PXR-null and humanized PXR mice.

CYP	hPXR Female	PXR-null Female	hPXR Male	PXR-null Male
Cyp2b9	2.20 ± 0.53	4.98 ± 1.02 b*	1.00 ± 0.64	0.05 ± 0.03 d**
Cyp2b10	0.65 ± 0.14	0.79 ± 0.40	1.00 ± 0.56	0.36 ± 0.11
Cyp2c29	0.59 ± 0.27	0.63 ± 0.11	1.00 ± 0.28	1.71 ± 0.62
Cyp3a11	0.22 ± 0.05	0.25 ± 0.06	1.00 ± 0.44	0.23 ± 0.06
Cyp3a41	9.71 ± 1.75	22.78 ± 4.78 b*	1.00 ± 0.87	0.34 ± 0.24 d**

Data is expressed as relative data ± SEM

^*P-value < 0.05 and

^**p-value < 0.01; indicate statistical significance by one-way ANOVA followed by Dunnett's multiple comparison test.

^aIndicates significant difference between hPXR female and hPXR male.

^bIndicates significant difference between hPXR female and PXR-null female mice.

^cIndicates significant difference between hPXR male and PXR-null male mice.

^dIndicates significant difference between PXR-null female and PXR-null male mice.