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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Mar 2;252(3):259–267. doi: 10.1016/j.taap.2011.02.017

Table 3.

Association of PXR status with hepatocyte hypertrophy in untreated and NP treated mice.

WTa PXR-nulla hPXRa
UT NP UT NP UT NP
0/6 4/6* 6/8 6/8 5/8 5/8

Data shown represents the number of mice that exhibited hepatocyte hypertrophy/total number of mice.

There were no differences between male and females, thus data was combined for analysis.

An asterisk indicates a significant difference between untreated and nonylphenol treated WT mice (p < 0.05) by a one-tailed Fisher's 2×2 test.