Table 3.
Association of PXR status with hepatocyte hypertrophy in untreated and NP treated mice.
WTa | PXR-nulla | hPXRa | |||
---|---|---|---|---|---|
UT | NP | UT | NP | UT | NP |
0/6 | 4/6* | 6/8 | 6/8 | 5/8 | 5/8 |
Data shown represents the number of mice that exhibited hepatocyte hypertrophy/total number of mice.
There were no differences between male and females, thus data was combined for analysis.
An asterisk indicates a significant difference between untreated and nonylphenol treated WT mice (p < 0.05) by a one-tailed Fisher's 2×2 test.