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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Expert Opin Emerg Drugs. 2008 Jun;13(2):295–308. doi: 10.1517/14728214.13.2.295

Table 2. Tumor antigens.

Antigen type Antigen Tumor type
Universal tumor antigens Telomerase, hTERT, survivin, mdm-2, CYP-1B1 All
Cancer testis antigens MAGE, BAGE, RAGE, GAGE, NY-ESO-1 Breast, prostate, testicular, bladder, melanoma, gastric, esophageal, hepatocellular, renal, lung, head and neck
Tissue-specific differentiation products PSA Prostate
Tyrosinase, Mart-1/Melan-A, gp100, trp-1, trp-2 Melanoma
Mutated gene products CDK-4-R24C Renal
β-catenin Colon
p53 Colon, breast, lung
k-ras Colon, pancreas, lung, esophageal
bcr-abl Leukemia
MUM-1 Leukemia
Overexpressed self-antigens HER-2/neu Breast
Proteinase-3 Leukemia
Mucin-1 Multiple myeloma, pancreas, gastric, breast
WT-1 Leukemia
MART-1/melan-A Melanoma
Mesothelin Pancreas, ovarian, peritoneal, mesothelioma
Idiotypes Ig, TCR Lymphoma