A rejecting homograft in a two-year-old child treated by transplantation for extra-hepatic biliary atresia is shown at top at the time of its removal, 68 days following insertion. (The liver weighed 250 gm at insertion, 880 at removal.) The child received a second homograft (lower photo); his subsequent course was extremely complicated, in part because of the large size of the second liver (which came from a seven-year-old donor), which severely crowded the abdominal cavity. Fortunately, swelling due to rejection was delayed for a month and eventually the child was able to eat a full diet. Although jaundiced, the child lived for one year after the second transplant and died of hepatic failure. (For gross appearance of first graft on pathologic examination see next page.)