Table 2.
Adjusted Vaccine Effectiveness (VE) Estimates for a Single Dose of AS03 Adjuvanted Pandemic (H1N1) 2009 Vaccine by Age Group, Risk Group and Whether Admitted to Hospital
| Analysis (No. of Observations) | VE (95% CI) |
|
| Onset ≥ 7 days since vaccination | Onset ≥ 14 days since vaccination | |
| Full model (1758)a | 60% (33% to 75%) | 60% (27% to 78%) |
| Simple model (1872)b | 61% (38% to 75%) | 62% (33% to 78%) |
| Risk group | ||
| Immunosuppressant disease/therapyb (504) | 29% (-53% to 67%) | 33% (-76% to 75%) |
| Others (1368) | 68% (41% to 82%) | 65% (29% to 83%) |
| Age groupb | ||
| 0–9 (502) | 37% (-50% to 74%) | 77% (11% to 94%) |
| 10–24 (351) | 100% (85% to 100%)c | 100% (80% to 100%)c |
| 25–49 (527) | 61% (-9% to 86%) | 22% (-153% to 76%) |
| 50+ (492) | 52% (-18% to 80%) | 41% (-71% to 80%) |
| Hospitalizedb | ||
| No (383) | 52% (-47% to 84%) | 68% (-60% to 94%) |
| Yes (1246) | 45% (3% to 69%) | 42% (-14% to 70%) |
NOTE. aAdjusting for age, period, sex, pregnancy, seasonal vaccine, immunosuppressant disease, immunosuppressant treatment, and chronic respiratory disease.
b
Adjusting for age and period only.
c
No cases exposed, so unadjusted exact 95% CI calculated.