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Model depicting the relationship between Noonan syndrome genotype (PTPN11 vs. SOS1 mutation) and language ability, with nonverbal cognitive ability as a mediator. a = effect of genotype on cognitive ability (mediator); b = effect of nonverbal cognitive ability on language ability (outcome variable); c′ = effect of genotype on language ability, controlling for nonverbal cognition. ns = not significant. **p < .01. ***p < .001.
