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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: J Immunol. 2008 Oct 1;181(7):4545–4559. doi: 10.4049/jimmunol.181.7.4545

FIGURE 4.

FIGURE 4

Quantitation of inflammatory cytokine production by PM-exposed DCs from Nrf2+/+ and Nrf2−/− mice. The secretion of immunoreactive IL-12p70 and IL-6 (A), IL-10 and TNF (B), as well as IL-18 (C) and VEGF (D) is shown. Bone marrow-derived DCs from the indicated strains were incubated with or without (Resting) particulate matter for 48 h, followed by analysis of cell-free supernatants by commercially available ELISA. Data are expressed as picograms per million cells and are the product of the mean ± SD of n = 6 sex- and age-matched mice per group.