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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Ann Rheum Dis. 2010 Nov 10;70(3):544–550. doi: 10.1136/ard.2010.132464

Figure 4. In vivo effect of poly(I:C) on EDN1, ECE1 and ICAM-1 expression.

Figure 4

Expression of EDN1 (a) and ECE1 (b), and ICAM-1 (c) by RT-PCR analysis of skin mRNA from C57BI/6 WT (n=10), C57BI/6/IFNAR−/− (n=8) and C57BI/6 TICAM−/− (n=10) mice one week after subcutaneous insertion of osmotic pumps containing poly(I:C) as described in methods. Fold-change shown in the graphs is normalized to mRNA expression by one of the control mice. Results presented are means ± SE and are representative of four independent experiments; * p<0.05; ** p<0.01.