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2DG-mediated oxidative stress induces activation of p53. (A) The protein levels of p53. After incubation with 20 mM 2DG for indicated time, cells were collected and processed for Western blot analysis. (B) The relative mRNA levels of SCO2 and TIGAR. The levels of mRNA were quantified by real-time RT-PCR. *p<0.05 compared with untreated control. Unt, untreated control.
