Table 1.

Polyphenols and botanical extracts tested against amyloid-beta toxicity

Polyphenol/plant name	Cell type	Effects	References
Apigenin	Cortical neurons	+	[122]
Baicalein	PC12 cells	+	[123]
			[124]
Biflavonoids	SH-SY5Y cells	+/−	[125]
Catechin	PC12 cells	+	[126]
			[127]
	Cortical neurons	+	[128]
Cocoa	PC12 cells	+	[127]
Cyanidin 3-O-glucoside	SH-SY5Y cells	+	[129]
Daidzein	Hippocampal neurons	+/−	[130]
EGCG	PC12 cells	+	[131]
	Hippocampal neurons	+	[132]
			[133]
Epicatechin	PC12 cells	+	[127]
			[124]
	Cortical neurons	+	[128]
	Hippocampal neurons	−	[133]
Gallic acid	Hippocampal neurons	+	[133]
Genistein	SH-SY5Y cells	+	[134]
	Hippocampal neurons	+/−	[130]
	Hippocampal neurons	+/−	[135]
	Cortical neurons	+	[136]
		−	[122]
Ginkgo biloba (EGb 761)	Hippocampal neurons	+	[137]
	N2a neuroblastoma	+	[138]
	SH-SY5Y cells	+	[139]
	PC12 cells	+/−	[140]
Grape seed	PC12 cells	+	[141]
			[142]
Hibifolin	Cortical neurons	+	[143]
	PC12 cells	+	[124]
Hypericum perforatum	Hippocampal neurons	+	[144]
Icaritin	Cortical neurons	+	[145]
Kaempferol	PC12 cells	+	[146]
			[124]
	Cortical neurons	+	[122]
Morin	HT22 neuroblastoma	+	[106]
Mulberry (leaf extract)	Hippocampal neurons	+	[147]
Myricetin	Cortical neurons	+	[148]
Naringenin	PC12 cells	+	[149]
		−	[124]
	Cortical neurons	−	[122]
Puerarin	PC12 cells	+	[150]
Pycnogenol	PC12 cells	+	[151]
Quercetin	Cortical neurons	+/−	[152]
		−	[122]
	HT22 neuroblastoma	+	[106]
Rhizoma acori graminei	PC12 cells	+	[153]
Scutellarin	PC12 cells	+	[124]
Smilacis chinae	Cortical neurons	+	[128]
Tea extracts	Hippocampal neurons	+	[133]