Figure 7.

Exogenous WNT4 expression phenotypes. A, Percentage proliferation was quantified for treatment with 15, 50, or 100 ng/well of exogenous WNT4 protein. Cells treated with 100 ng/well of exogenous WNT4 protein hyperproliferated compared to heat-inactivated WNT4 and cells cultured in unsupplemented media. B, Treatment with exogenous WNT5a also caused hyperproliferation; however, CEBPG siRNA in combination with exogenous WNT4 treatment inhibited proliferation similarly to CEBPG siRNA treatment alone.