Table 2.

Levels of psychosine and sphingosine in the brain.

	Psychosine (pmol/mg protein)	Sphingosine (pmol/mg protein)
Wild type	28 ± 4	104 ± 11
op	27 ± 5	107 ± 18
twi	328 ± 52 ***	79 ± 16 **
twi + op	236 ± 65 **, †	65 ± 8 ***, †

Values are expressed as mean ± SD from three animals per group at 45 d old. Values for each animal were an average of measurements from the right and left brain hemispheres.

**p < 0.001 and

***p < 0.0001 versus wild type group;

^†p < 0.05 versus twi group; one-way ANOVA followed by Scheffé's F post-hoc test.