Table II.

Binding affinities of TV9 and its mimic peptides to HLA-A2 supertype molecules. Dash indicates IC₅₀ >10,000 nM.

Peptide	Sequence									# Substitutions	IC50 (nM)
											A*0201	A*0202	A*0203	A*0206	A*6802
TV9	T	L	N	A	W	V	K	V	V	Native	701	179	108	1,965	23,937
TV9p5	K	I	N	A	W	I	K	G	V	4	536	433	10	224	36,760
TV9p6	K	I	N	A	W	I	K	V	V	3	5,120	2,950	56	13,449	--
TV9p29	T	I	N	A	W	I	K	G	V	3	1,062	706	15	2,248	269
TV9p30	T	I	N	A	W	I	K	V	V	2	4,228	1,835	112	12,581	6,218
SL9	S	L	Y	N	T	V	A	T	L	Native	367	79	19	--	--