Table IV.
TCRBV and TCRJ usage, CDR3 amino acid sequence and percent frequency of TV9-specific CD8+ T cell clonotypes in parallel CTL cultures.
| CTLs | HLA Class I Alleles | Vβ (Arden) | IMGT TRB | CDR3 | TRBJ | Frequency |
|---|---|---|---|---|---|---|
| TV9-7 | A*0201,A11 B18,B27 | 13 | 6-1 | CASSEEGAWNTGELF | 2-2 | 90 |
| 9 | 3-1 | CASSHTSGGLKDTQY | 2–3 | 10 | ||
| TV9p6-7 | 7 | 4-3 | CASSPRGDWEEKAGELF | 2-2 | 77 | |
| 13 | 6-1 | CASSEEGAWNTGELF | 2-2 | 15 | ||
| 4 | 29-1 | CSVEDPDRGYEQY | 2–7 | 8 | ||
| TV9-6 | A*0201,A29 B40,B44 | 14 | 27 | CASSRRGDGFQPQH | 1–5 | 36 |
| 13 | 6-6 | CASRDFYNEQF | 2-1 | 29 | ||
| 2 | 20-1 | CSAFSSGTGGVTGELF | 2-2 | 14 | ||
| 7 | 4-3 | CASSQDPSPSTDTQY | 2–3 | 7 | ||
| 6 | 7–8 | CASSLWGLAPDNEQF | 2-1 | 7 | ||
| 14 | 27 | CASSLWGGPMETQY | 2–5 | 7 | ||
| TV9p6-6 | 2 | 20-1 | CSAFSSGTGGVTGELF | 2-2 | 82 | |
| 6 | 7-2 | CASSLVPQGEEQY | 2–7 | 6 | ||
| 2 | 20-1 | CSAFSSGTGGVTGEPF | 2-2 | 6 | ||
| 2 | 20-1 | CSAFSSGTEGVTGELF | 2-2 | 6 | ||
| TV9-9 | A*0201,A24 B15,B40 | 6 | 7-2 | CASSLVPQGEEQY | 2–7 | 88 |
| 6 | 7-2 | CASSLVPQGEEPY | 2–7 | 12 | ||
| TV9-3 | A2 | 3 | 28-0 | CASSYRGQSYEQY | 2–7 | 94 |
| 4 | 29-1 | CSGRGDSYTEAF | 1-1 | 4 | ||
| 5, 31 | 5–8 | CASSEYRGPSSYEQY | 2–7 | 1 | ||
| 3 | 28-0 | CASSCRGQSYEQY | 2–7 | 1 | ||
| TV9-2 | A*0201 B15,B40 | 2 | 20-1 | CSARDAGGDYGYT | 1–2 | 69 |
| 8 | 12-4 | CASSDTGELF | 2-2 | 26 | ||
| 9 | 3-1 | CASSQVKIGQGNEKLF | 1–4 | 6 | ||
| TV9p6-2 | 2 | 20-1 | CSASRDSYEQY | 2–7 | 100 | |