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. Author manuscript; available in PMC: 2012 Apr 22.
Published in final edited form as: Brain Res. 2011 Mar 2;1386:118–126. doi: 10.1016/j.brainres.2011.02.081

Table 1.

Characteristics of lumbosacral spinal dorsal horn neurons excited by urinary bladder distension (UBD) in intact, female rats

Group N Class 1 Class 2/WDR Class 3/NS RF Size (l:m:s)
NFS Total 44
 Type I 22 0 20 2 0:11:11
 Type II 22 0 7 15 9:13:0

AFS Total 46
 Type I 19 0 16 3 0:11:8
 Type II 27 0 17 10 11:14:2

CFS Total 40
 Type I 8 0 7 1 0:3:5
 Type II 32 0 21 11 19:13:0

Rats were exposed to one of three conditions: acute footshock (AFS), chronic footshock (CFS) or to no footshock (NFS). All neurons were excited by a 60 mmHg, 20 sec phasic constant pressure UBD. Neurons were further classified according to the following: (1) by counter-irritation effects: Type I neurons had spontaneous activity inhibited >20% by a non-segmental noxious cutaneous stimulus; Type II neurons were not similarly inhibited; (2) by receptive field (RF): Class 1 neurons were excited only by non-noxious stimuli; Class 2/wide dynamic range (WDR) neurons were excited by both noxious and nonnoxious cutaneous stimuli; Class 3/nociceptive specific (NS) neurons responded only to noxious cutaneous stimuli; and (3) by RF size: large (l – hind quarter or > hind quarter with contralateral input); medium (m – long axis > 4 cm, including part of hind limb but not tail); small (s – long axis < 4 cm).