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. 2011 Feb 10;32(5):695–702. doi: 10.1093/carcin/bgr027

Fig. 3.

Fig. 3.

Macrophage induction of COX-2 in breast cancer cells is Src dependent. (A) Levels of phospho-Src (p∼Src) and Src in HCC1954 cells cocultured with THP-1 cells or treated with 1 h coculture CM were determined. (B) Levels of p∼Src and Src in HCC1954 cells cocultured with THP-1 cells or treated with 1 h coculture CM in the absence or presence of DPI for 1 h were determined. (C) Levels of COX-2 and β-actin in HCC1954 cells cocultured with THP-1 cells or treated with 1 h coculture CM in the absence or presence of PP1 and PP2 for 6 h were determined. (D) Levels of Src, COX-2 and β-actin in HCC1954 cells transfected with Src siRNA and cocultured with THP-1 cells for 6 h were determined.