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Effect of CDDO on metastasis of prostate cancer. (A) A 25-week-old control TRAMP mouse showing highly enlarged pelvic lymph nodes because of tumor metastasis. (B) H&E-stained sections of liver (a), lung (b), kidney (c) and pelvic lymph node (d) of 25-week-old control TRAMP mice showing metastatic lesions (×250). (C) Shows the incidence of metastasis in different organs in control and CDDO-treated 25-week-old TRAMP mice.
