Figure 6.

Mesenchymal CFUs in the bronchoalveolar lavage (BAL) as predictors of bronchiolitis obliterans syndrome (BOS) onset in lung transplant recipients. (A) Kaplan-Meier curve demonstrating time to BOS in lung transplant recipients grouped by number of mesenchymal CFUs in BAL (CFU ≥10, dashed line; CFU <10, solid line). (B) CFU-group specific adjusted time to BOS plots based on survival estimates obtained using hazards estimated with Cox models adjusted for average patient profile. Average covariate profile is as follows: time from transplant to BAL = 1.74 year; probability of being male = 52%; probability of histologic diagnosis of acute rejection = 11.9%, lymphocytic bronchitis = 10%; probability of pretransplant diagnosis of idiopathic pulmonary fibrosis = 32.4%, chronic obstructive pulmonary disease = 39.9%, cystic fibrosis = 13.9%; probability of single lung transplantation = 57.8%.