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Measurement of Aβ1–40 and Aβ1–42 from conditioned media of HEK293 APPsw overexpressing SorCS1 isoforms. Aβ levels normalized to total protein were measured. Data shown as percentages of control values (XL4; n = 3 per experiment, 3 independent experiments). APP = amyloid precursor protein; APPsw = amyloid precursor protein Swedish mutation; FL-APP = APP holoprotein; XL4 = empty vector.
