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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Biochem Biophys Res Commun. 2010 Mar 10;394(2):434–438. doi: 10.1016/j.bbrc.2010.03.048

Figure 4. Inhibition of inward-rectifier Cl currents by ClC-2 antibody.

Figure 4

Summary I-V relationships; voltage protocol as in Figure 1. Currents recorded with antibody (3 µg/ml) raised against an intracellular epitope of ClC-2 added to the pipette solution (Anti-ClC-2 Ab; up triangles) were significantly reduced at negative membrane voltages compared to those serving as “Control” with heat-inactivated antibody (down triangles).