Table 1.
Group | n | Mean Ileal Macrophages | Mean Hepatic IL-1β |
---|---|---|---|
NEC WT | 30 | 28.9±3.7* | 32.3±3.3* |
NEC IL-18−/− | 34 | 12.2±2.3 | 10.5±3.0 |
DF WT | 10 | 15.9±3.5 | 9.8±4.1 |
DF IL-18−/− | 10 | 13.2±4.6 | 8.1±2.5 |
NEC WT, wild-type mice subjected to necrotizing enterocolitis (NEC) by formula feeding and cold stress; NEC IL-18−/−, IL-18 knockout mice subjected to NEC protocol; DF WT, dam-fed wild-type mice; DF IL-18−/−, dam-fed IL-18 knockout mice.
P ≤ 0.01 vs. NEC IL-18−/−, DF WT, and DF IL-18−/− groups.