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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Cell Cycle. 2010 Jan 29;9(2):389–397. doi: 10.4161/cc.9.2.10475

Figure 1.

Figure 1

The components of IRIF are reorganized during the cell cycle. HeLa cells were synchronized by colcemid, exposed to 1 Gy IR and fixed after 30 min incubation. Mitotic stages were classified by DAPI staining. (A) Immunostaining for γH2AX and 53BP1. I-III refer to enlargements of the noted areas. (B) Immunostaining for γH2AX and MDC1. (C) Fraction of γH2AX foci colocalized with 53BP1 (left) or MDC1 (right).