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. 2011 Mar 31;103(9):714–736. doi: 10.1093/jnci/djr077

Table 7.

Age-standardized rates and counts for tumors of the brain and other nervous system (nonmalignant and malignant), by histological grouping, race, and sex, North American Association of Central Cancer Registries (NAACCR) combined, 2004–2007*

Sex Histological group All races
White
Black
API
AI/AN CHSDA
Hispanic
Non-Hispanic
Rate Count Rate Count Rate Count Rate Count Rate Count Rate Count Rate Count
Men and women Brain and other nervous system 18.9 213 525 19.0 181 790 17.7 20 158 13.5 6440 15.3 831 17.8 20 464 19.1 193 061
    Tumors of neuroepithelial tissue 6.5 73 467 7.0 66 083 3.7 4573 3.2 1601 4.3 257 5.1 6613 6.7 66 854
        Pilocytic astrocytoma 0.3 3534 0.4 2989 0.2 332 0.2 85 0.4 31 0.2 502 0.3 3032
  Diffuse and anaplastic astrocytoma§ 1.0 10 851 1.1 9779 0.5 633 0.5 256 0.7 45 0.7 985 1.0 9866
        Glioblastoma 3.2 36 613 3.4 33 864 1.6 1798 1.4 634 1.8 86 2.4 2311 3.3 34 302
        Oligodendroglioma and anaplastic oligodendroglioma 0.4 4452 0.4 3995 0.2 237 0.2 122 0.3 15 0.3 452 0.4 4000
        Mixed glioma 0.2 2203 0.2 1978 0.1 115 0.1 67 0.2 12 0.2 245 0.2 1958
        Glioma malignant, NOS 0.4 4809 0.5 4125 0.3 426 0.3 134 0.3 22 0.4 573 0.4 4236
        Embryonal/primitive/medulloblastoma 0.2 2168 0.2 1813 0.1 226 0.1 77 0.2 15 0.2 441 0.2 1727
  All other tumors of neuroepithelial tissue 0.8 8837 0.8 7540 0.6 806 0.4 226 0.4 31 0.6 1104 0.8 7733
    Tumors of cranial and spinal nerves 1.7 19 062 1.7 16 697 0.7 861 1.5 782 1.0 56 1.3 1535 1.7 17 527
        Nerve sheath 1.7 19 057 1.7 16 693 0.7 861 1.5 781 1.0 56 1.3 1535 1.7 17 522
            Acoustic neuromas 1.1 12 033 1.1 10 647 0.4 433 0.9 494 0.4 23 0.8 888 1.1 11 145
            All other nerve sheath 0.6 7024 0.6 6046 0.3 428 0.5 287 0.5 33 0.5 647 0.6 6377
    Tumors of meninges 6.8 77 799 6.7 65 175 7.8 8275 5.7 2551 5.9 279 6.9 6598 6.8 71 201
        Meningioma 6.6 75 318 6.4 63 063 7.6 8069 5.5 2447 5.7 266 6.7 6298 6.6 69 020
  All other tumors of meninges 0.2 2481 0.2 2112 0.2 206 0.2 104 0.2 13 0.2 300 0.2 2181
    Germ cell tumors and cysts 0.1 915 0.1 736 0.1 84 0.1 63 0.1 6 0.1 188 0.1 727
    Tumors of sellar region 2.7 30 205 2.4 22 836 4.4 5144 2.3 1162 3.0 180 3.3 4244 2.6 25 961
 All other brain# 1.1 12 077 1.1 10 263 1.1 1221 0.7 281 1.0 53 1.2 1286 1.0 10 791
Lymphomas and hematopoietic neoplasms of the brain and ONS 0.5 5182 0.5 4410 0.4 504 0.4 203 0.4 20 0.5 545 0.5 4637
Men Brain and other nervous system 17.3 90 870 17.6 78 476 15.5 7694 11.6 2583 12.8 328 15.1 8445 17.7 82 425
    Tumors of neuroepithelial tissue 7.7 40 820 8.2 36 917 4.2 2342 3.8 883 4.9 141 5.8 3620 8.0 37 200
        Pilocytic astrocytoma 0.3 1834 0.4 1562 0.2 158 0.2 43 0.4 14 0.2 265 0.4 1569
  Diffuse and anaplastic astrocytoma§ 1.1 6013 1.2 5479 0.5 309 0.6 134 0.6 18 0.8 540 1.2 5473
        Glioblastoma 4.0 20 841 4.3 19 330 2.0 958 1.8 375 2.1 50 2.9 1293 4.1 19 548
        Oligodendroglioma and anaplastic oligodendroglioma 0.5 2467 0.5 2197 0.2 135 0.3 74 0.3 9 0.3 224 0.5 2243
        Mixed glioma 0.2 1277 0.3 1147 0.1 65 0.1 37 0.2 6 0.2 139 0.2 1138
        Glioma malignant, NOS 0.5 2462 0.5 2152 0.3 192 0.2 60 0.3 12 0.4 293 0.5 2169
        Embryonal/primitive/medulloblastoma 0.2 1233 0.2 1032 0.2 122 0.2 44 0.3 11 0.2 269 0.2 964
  All other tumors of neuroepithelial tissue 0.9 4693 0.9 4018 0.6 403 0.4 116 0.7 21 0.7 597 0.9 4096
    Tumors of cranial and spinal nerves 1.7 9170 1.7 8044 0.7 395 1.5 359 1.0 28 1.2 702 1.8 8468
        Nerve sheath 1.7 9168 1.7 8042 0.7 395 1.5 359 1.0 28 1.2 702 1.8 8466
            Acoustic neuromas 1.0 5704 1.1 5064 0.3 187 0.9 221 0.4 10 0.7 395 1.1 5309
            All other nerve sheath 0.6 3464 0.7 2978 0.3 208 0.5 138 0.6 18 0.5 307 0.7 3157
    Tumors of meninges 4.2 21 177 4.1 17 823 5.0 2205 3.3 663 3.6 73 3.8 1689 4.2 19 488
        Meningioma 3.9 19 820 3.8 16 661 4.8 2107 3.1 602 3.4 68 3.6 1529 4.0 18 291
  All other tumors of meninges 0.2 1357 0.3 1162 0.2 98 0.2 61 ** ** 0.2 160 0.3 1197
    Germ cell tumors and cysts 0.1 648 0.1 526 0.1 51 0.2 45 ** ** 0.1 146 0.1 502
    Tumors of sellar region 2.6 13 665 2.3 10 555 4.4 2166 2.3 524 2.6 65 3.0 1677 2.5 11 988
 All other brain# 1.1 5390 1.1 4611 1.2 535 0.6 109 0.6 17 1.2 611 1.1 4779
Lymphomas and hematopoietic neoplasms of the brain and ONS 0.5 2802 0.5 2379 0.5 279 0.5 105 0.5 13 0.6 340 0.5 2462
Women Brain and other nervous system 20.3 122 655 20.3 103 314 19.5 12 464 15.0 3857 17.6 503 20.4 12 019 20.4 110 636
    Tumors of neuroepithelial tissue 5.6 32 647 5.9 29 166 3.3 2231 2.7 718 3.7 116 4.5 2993 5.7 29 654
        Pilocytic astrocytoma 0.3 1700 0.3 1427 0.2 174 0.2 42 0.4 17 0.2 237 0.3 1463
  Diffuse and anaplastic astrocytoma§ 0.8 4838 0.9 4300 0.5 324 0.4 122 0.8 27 0.7 445 0.9 4393
        Glioblastoma 2.5 15 772 2.7 14 534 1.4 840 1.0 259 1.5 36 2.0 1018 2.6 14 754
        Oligodendroglioma and anaplastic oligodendroglioma 0.4 1985 0.4 1798 0.1 102 0.2 48 0.2 6 0.3 228 0.4 1757
        Mixed glioma 0.2 926 0.2 831 0.1 50 0.1 30 0.2 6 0.1 106 0.2 820
        Glioma malignant, NOS 0.4 2347 0.4 1973 0.3 234 0.3 74 0.3 10 0.3 280 0.4 2067
        Embryonal/primitive/medulloblastoma 0.2 935 0.2 781 0.1 104 0.1 33 ** ** 0.2 172 0.2 763
  All other tumors of neuroepithelial tissue 0.7 4144 0.8 3522 0.5 403 0.4 110 0.2 10 0.6 507 0.8 3637
    Tumors of cranial and spinal nerves 1.7 9892 1.8 8653 0.7 466 1.5 423 0.9 28 1.4 833 1.7 9059
        Nerve sheath 1.7 9889 1.8 8651 0.7 466 1.5 422 0.9 28 1.4 833 1.7 9056
            Acoustic neuromas 1.1 6329 1.1 5583 0.4 246 1.0 273 0.5 13 0.8 493 1.1 5836
            All other nerve sheath 0.6 3560 0.6 3068 0.3 220 0.5 149 0.5 15 0.5 340 0.6 3220
    Tumors of meninges 9.1 56 622 8.9 47 352 9.9 6070 7.6 1888 7.9 206 9.5 4909 9.1 51 713
        Meningioma 8.9 55 498 8.7 46 402 9.7 5962 7.5 1845 7.7 198 9.3 4769 8.9 50 729
  All other tumors of meninges 0.2 1124 0.2 950 0.2 108 0.2 43 0.2 8 0.2 140 0.2 984
    Germ cell tumors and cysts 0.1 267 0.0 210 0.0 33 0.1 18 ** ** 0.1 42 0.1 225
    Tumors of sellar region 2.9 16 540 2.6 12 281 4.5 2978 2.3 638 3.5 115 3.7 2567 2.8 13 973
 All other brain# 1.1 6687 1.0 5652 1.1 686 0.7 172 1.4 36 1.2 675 1.0 6012
Lymphomas and hematopoietic neoplasms of the brain and ONS 0.4 2380 0.4 2031 0.3 225 0.4 98 0.3 7 0.4 205 0.4 2175
*

AI/AN = American Indian/Alaska Native; API = Asian/Pacific Islander; CHSDA = Contract Health Services Delivery Area; IHS = Indian Health Service; NOS = not otherwise specified; ONS = other nervous system. Source: NAACCR Combined—National Program of Cancer Registries and Surveillance, Epidemiology, and End Results Program areas reported by NAACCR as meeting high-quality incidence data standards for 2003–2007 (46 states): Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nebraska, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming. The table excludes cancer cases that were identified as having invalid site/histology combinations.

The site grouping “Brain and ONS” includes cancer cases with primary sites C70.0–C72.9 and C75.1–C75.3. The category “Lymphomas and hematopoietic neoplasms of the brain and ONS” refers to those lymphomas and hematopoietic neoplasms with a primary site of C70.0–C72.9 and C75.1–C75.3 as defined in Central Brain Tumor Registry of the United States (CBTRUS) (2010). CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2004–2006.

Incidence rates are per 100 000 persons and were age standardized to the 2000 US standard population (19 age groups: <1, 1–4, 5–9, 10–14, … , 80–84, ≥85 years, Census P25–1130).

§

Diffuse astrocytoma (as defined by World Health Organization 2007) includes the following histological groups: protoplasmic and fibrillary astrocytoma, astrocytoma NOS, and gemistocytic astrocytomas (9411).

All other tumors of neuroepithelial tissue includes the following histological groups: unique astrocytoma variants, ependymoma variants, choroid plexus, neuroepithelial, and pineal parenchymal, nonmalignant and malignant neuronal/glial, neuronal and mixed.

All other tumors of meninges include the following histological groups: other mesenchymal, hemangioblastoma.

#

All other brain includes the following histological groups: chordoma/chondrosarcoma, hemangioma, unspecified neoplasms, and all other histologies which could not be classified above.

**

Statistic not displayed because less than six cancer cases in this category.