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. 2011 May 3;6(5):e19240. doi: 10.1371/journal.pone.0019240

Figure 3. Verification of the novelty of signalogs (protein – signaling pathway annotations).

Figure 3

a) Classification of signalog proteins based on their known properties in the literature found by manual curation and searches in PubMed, UniProt, GO, Wormbase, Flybase, iHOP, and Chilibot [32]–[35]. b–c) Comparison of signalog and interolog data between Signalink and one of the WI8, DroID or HomoMINT databases. The signalog proteins and possible interologs that are only present in SignaLink have not been predicted by previous orthology based (interolog) studies. This underscores the novelty of the signalogs. For details on interologs predicted from SignaLink data, see the main text.