Table 2. Differentially Expressed Genes in Recurrent NSCLC (Group R) Compared to Non-Recurrent NSCLC (Group NR) – Differential analysis based on P values <0.001.
| Gene Symbol | Source id | Fold Change | Welch's T-test Log(Signal) | Description |
|---|---|---|---|---|
| CYP3A5 | 205765_at | 18.66 | 1.30E-04 | Cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DPM3 | 219373_at | 1.87 | 4.60E-04 | Dolichyl-phosphate mannosyltransferase polypeptide 3 |
| NES | 218678_at | 1.85 | 2.20E-04 | Nestin |
| TACSTD1 | 201839_s_at | 1.84 | 5.80E-04 | Tumor-associated calcium signal transducer 1 |
| DECR1 | 202447_at | 1.74 | 1.50E-04 | 2,4-dienoyl CoA reductase 1, mitochondrial |
| DBN1 | 202806_at | 1.71 | 6.40E-04 | Drebrin 1 |
| KIAA1598 | 221802_s_at | 1.62 | 5.30E-04 | KIAA1598 |
| CACNB3 | 34726_at | 1.58 | 1.10E-04 | Calcium channel, voltage-dependent, beta 3 subunit |
| PP591 | 212541_at | 1.56 | 8.40E-04 | FAD-synthetase |
| PSMD4 | 200882_s_at | 1.56 | 6.20E-04 | Proteasome 26S subunit, non-ATPase, 4 |
| DNAJB12 | 202866_at | 1.52 | 3.50E-04 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| MAN2A2 | 202032_s_at | 1.52 | 2.60E-04 | Mannosidase, alpha, class 2A, member 2 |
| D2LIC | 203763_at | 1.51 | 0.001 | Dynein 2 light intermediate chain |
| DKFZp566O084 | 220690_s_at | 1.51 | 7.00E-05 | DKFZP566O084 protein |
| FLJ20343 | 217964_at | 1.46 | 1.00E-05 | Hypothetical protein FLJ20343 |
| BCAP31 | 200837_at | 1.45 | 3.00E-04 | B-cell receptor-associated protein 31 |
| SMBP | 217758_s_at | 1.42 | 8.10E-04 | SM-11044 binding protein |
| ECHS1 | 201135_at | 1.39 | 8.80E-04 | Enoyl Coenzyme A hydratase, short chain, 1 |
| SCRIB | 212556_at | 1.38 | 5.00E-04 | Scribbled homolog |
| SUPV3L1 | 212894_at | 1.35 | 8.40E-04 | Suppressor of var1, 3-like 1 |
| XPNPEP1 | 209045_at | 1.35 | 9.90E-04 | X-prolyl aminopeptidase 1 |
| C10orf119 | 217905_at | 1.33 | 4.00E-04 | Chromosome 10 open reading frame 119 |
| ACTR1A | 200721_s_at | 1.32 | 3.30E-04 | ARP1 actin-related protein 1 homolog A |
| PSMB4 | 202244_at | 1.23 | 9.80E-04 | Proteasome subunit, beta type, 4 |
| TEX27 | 218020_s_at | -1.19 | 5.90E-04 | Testis expressed sequence 27 |
| MLL | 212076_at | -1.24 | 6.50E-04 | Myeloid/lymphoid or mixed-lineage leukemia |
| ENO1 | 216554_s_at | -1.28 | 4.50E-04 | Enolase 1 |
| C6orf69 | 214849_at | -1.35 | 8.30E-04 | Chromosome 6 open reading frame 69 |
| SPAG9 | 212470_at | -1.37 | 2.40E-04 | Sperm associated antigen 9 |
| STK17B | 217503_at | -1.37 | 6.50E-04 | Serine/threonine kinase 17b |
| FLJ10996 | 219774_at | -1.38 | 9.20E-04 | Hypothetical protein FLJ10996 |
| C14orf118 | 219720_s_at | -1.41 | 8.00E-05 | Chromosome 14 open reading frame 118 |
| TBC1D5 | 201815_s_at | -1.41 | 2.20E-04 | TBC1 domain family, member 5 |
| CLN5 | 204085_s_at | -1.43 | 9.10E-04 | Ceroid-lipofuscinosis, neuronal 5 |
| AHCYL1 | 207464_at | -1.45 | 4.10E-04 | S-adenosylhomocysteine hydrolase-like 1 |
| STAT2 | 205170_at | -1.48 | 1.10E-04 | Signal transducer and activator of transcription 2 |
| ATF7IP | 218987_at | -1.52 | 1.30E-04 | Activating transcription factor 7 interacting protein |
| CD44 | 210916_s_at | -1.62 | 4.20E-04 | CD44 antigen |
| HIPK3 | 210148_at | -1.72 | 1.80E-04 | Homeodomain interacting protein kinase 3 |
| HIPK3 | 207764_s_at | -1.85 | 1.40E-04 | Homeodomain interacting protein kinase 3 |
| CD44 | 204490_s_at | -1.88 | 2.50E-04 | CD44 antigen |
| CCND2 | 200952_s_at | -1.89 | 1.90E-04 | Cyclin D2 |
| CD44 | 209835_x_at | -1.99 | 5.40E-04 | CD44 antigen |
| TRA@ | 209671_x_at | -2.1 | 3.10E-04 | T cell receptor alpha locus |
| CD44 | 212014_x_at | -2.12 | 8.80E-04 | CD44 antigen |
| HLA-DOA | 206313_at | -2.2 | 1.60E-04 | Major histocompatibility complex, class II, DO alpha |
| SOD2 | 221477_s_at | -2.25 | 6.60E-04 | HepG2 3′ region MboI cDNA, clone hmd2a08m3 |
| SOD2 | 216841_s_at | -2.52 | 7.40E-04 | Superoxide dismutase 2, mitochondrial |
| SOD2 | 215223_s_at | -2.77 | 8.80E-04 | Superoxide dismutase 2, mitochondrial |
| CCND2 | 200951_s_at | -3.49 | 4.50E-04 | Cyclin D2 |
| CXCL13 | 205242_at | -5.31 | 4.00E-04 | Chemokine (C-X-C motif) ligand 13 |
Affymetrix source id is indicated because of the identification of multiple Affymetrix probes for several genes, including CD44, SOD2, HIPK3 and CCND2.