Wound closure is inhibited by resveratrol. Confluent B16F10 cells were grown in serum-containing media, scratched and the media then replaced without serum but containing DMSO or 100 µM resveratrol. Representative images from three separate experiments show wounds at 8hrs (a, b) and 17hrs (c, d) with DMSO (a, c) or resveratrol (b, d).