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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Melanoma Res. 2011 Jun;21(3):180–187. doi: 10.1097/CMR.0b013e3283456dfc

Figure 5.

Figure 5

Affect of cell migration in dominant-negative Akt or over-expressing stable cell lines in the presence or absence of resveratrol. A) Cells expressing dominant-negative Akt are less invasive. In a transwell assay, photomicrographs of 4 different fields per condition were used to count the number of migrating cells incubated with DMSO, 25 µM resveratrol or 50 µM resveratrol. Results are representative of three separate experiments. Mean values ± S.D. B) Over-expression of wild-type Akt1 rescues cells from resveratrol-mediated inhibition of invasiveness. In a transwell assay, photomicrographs of 4 different fields per condition were used to count the number of migrating cells incubated with DMSO or 100 µM resveratrol. Images are representative of three separate experiments. Mean values ± S.D.