Figure 1. Ribavirin reduces proliferation and clonogenic survival of breast cancer cells.

(A) Breast cancer cell lines (top) and primary normal breast cells (bottom) were cultured in the absence or presence of ribavirin at the indicated concentrations for 7 days, and the number of cells was determined as described in Materials and Methods. (B) Anchorage-dependent clonogenic potential was assessed in cells cultured in the absence or presence of ribavirin for 14 days.