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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Clin Cancer Res. 2011 Feb 9;17(9):2679–2692. doi: 10.1158/1078-0432.CCR-10-2058

Figure 3. The anatomy of 11q deletions in CLL does not explain differences in INSR expression.

Figure 3

A: Heatmap display of copy number estimates for parts of chromosome 11 (blue: copy loss; red: copy gain) based on SNP 6.0 array profiling. The location of the ATM-centric FISH probe used clinically is indicated. Cases are ordered by degree of INSR expression. B: Summary of Q-PCR-based normalized INSR mRNA levels (ΔCt INSR-GAPDH values) and FACS-based INSR protein expression levels for the CLL cases with 11q deletions marked in panel A.