Table 2.
TABLE 2a. Genes showing significant changes in expression associated with AVP treatment. | ||
---|---|---|
Gene | Fold change | Function |
CASP1 | -3.40 | Cleave and activate IL1 |
CST7 | -2.50 | Immune response |
LILRB1 | -2.25 | Immune response |
SPA17 | -1.68 | Immune cell migration and metastasis |
LTB | 1.56 | Immune response |
IL13 | -1.43 | Interleukin 13 |
IL7 | -1.42 | Interleukin 7 |
CEACAM8 | -1.37 | Immune response |
DEFA5 | -1.36 | Antimicrobial humoral response |
CXCL16 | -1.36 | Chemotaxis, immune response |
IL10B | -1.31 | Interleukin 10 beta |
MHC2TA | -1.30 | Parasite perception, immune response |
TABLE 2b. Genes showing consistent and significant changes in expression associated with AVP treatment in at least 3 of the 4 males. | ||
---|---|---|
Gene | Fold change | Function |
IGJ | -2.77 | Immunoglobulin J chain, activation of B lymphocytes |
IGK | -2.66 | Immunoglobulin K chain |
IGHA1 | -2.51 | Immunoglobulin heavy constant alpha 1 |
IL1B | -2.40 | Interleukin 1 beta |
IL16 | -2.20 | Interleukin 16, chemoattractant factor |
NFIL3 | -1.90 | Nuclear factor, interleukin 3 |
CRHR1 | -1.86 | Corticotropin releasing hormone receptor 1 |
CD94 | -1.86 | Antigen preferentially expressed on natural killer cells |
TNFα-P6 | -1.64 | Tumor necrosis factor alpha-induced protein 6 |
IL10RA | -1.64 | Interleukin 10 receptor activity |
TNFSF13B | -1.62 | Tumor necrosis factor receptor binding, B cell activation and differentiation |
IL6ST | -1.60 | Interleukin 6 signal transducer |
IL15 | -1.46 | Interleukin 15, T and natural killer cell activation |
A2M | -1.44 | Cytokine transporter |