Table 1.
Various studies about incidence of deep vein thrombosis in Indian patients after major orthopedic trauma
| Studies | Study design | Orthopedic trauma | Diagnostic modalities | Prophylaxis | Incidence (%) | Remarks |
|---|---|---|---|---|---|---|
| Sharma et al.,11 2002 | Prospective | 112 hip fractures | Color Doppler | Nil | 19.6 (22/112) | High incidence; advised thromboprophylaxis |
| Agarwala et al.,14 2003 | Prospective | 18 proximal femoral fractures | Venography | + LMWH (Dalteparin) | 45.4 (5/11) in prophylaxis group; 71.4 (5/7) in non-prophylaxis group | High incidence; advised thromboprophylaxis |
| Bhan et al.,24 2004 | Prospective | 15 lower-limb fractures + 10 spinal injuries | Doppler ultrasound | Mechanical prophylaxis (lymphavision) | 0 (0/25) | Advised mechanical prophylaxis |
| Agarwala et al.,15 2005 | Prospective | 12 patients with femoral neck fracture | Color Doppler | LMWH (Dalteparin) | 0 (0/12) | Advised prophylaxis |
| Maini et al.,17 2006 | Retrospective | Femoral neck fractures (271 patients) | NA | Initial 5 years: no prophylaxis; next 5 years: prophylaxis | 9.9 (20 in non-prophylaxis group and 5 in prophylaxis-receiving group). No exact data about the number of patients in each group | Significant reduction with prophylaxis |
| Bagaria et al.,26 2006 | Prospective | 102 proximal femur fractures | Duplex ultrasonography | Nil | 6.8 (7/102) | Low incidence; advised thromboprophylaxis in high-risk group |
| Rajgopalan,27 2007 | Prospective | 77 femur fractures | Color Doppler ultrasound | LMWH (Dalteparin) | 6.49 (5/77) | Advised prophylaxis |
| Mavalankar et al.,21 2007 | Prospective | 55 patients with lower-limb fractures | Duplex ultrasonography | Nil | 10.91 (6/55) | Advised prophylaxis in high-risk patients |
| Saraf et al.,25 2007 | Prospective | Acute spinal cord injury (70 patients) | 42, color Doppler; 28, venography | Nil | 10 (7/70) | Low incidence; however, advised routine screening. Clinical suspicion is inadequate |
| Agarwal et al.,23 2009 | Prospective | Acute spinal cord injury (297 patients) | Color Doppler | 166 with prophylaxis; 131, no prophylaxis | 1.81 (3/166) in prophylaxis group; 3.05 (4/131) in non-prophylaxis group | Low incidence, no significant effect of prophylactic heparin therapy |