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. Author manuscript; available in PMC: 2011 May 4.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2010 MAY-JUN;2(3):277–292. doi: 10.1002/wsbm.61

FIGURE 7.

FIGURE 7

Framework for the integration of omic data for the discovery of subnetworks implicated in complex phenotypes. Proteomic screening provides functional data for a limited set of proteins, transcriptomic screening provides genome-scale data on mRNA expression, and curated or high-throughput protein–protein interactions provide a framework for the integration of these two complementary, valuable sources of data. This framework also illustrates how researchers can couple specific data sets generated in their labs with public data to broaden the scope of their analyses.