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Inhibited tumor cell growth in TPM3 knockdown HepG2 (A) and SNU-475 (B). Top plots of A and B are colony formation assay results. Bottom plots are soft agar assay results. In both the colony formation and anchorage independent growth assays, the number of colonies were counted in siTPM and siNEG plates. siTPM3, siTMP3 transfected HCC cell line; siNEG, negative oligonucleotide (siNEG) transfected HCC cell line. * represents P value < 0.05.
