Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Jun 16;10:294. doi: 10.1186/1471-2407-10-294

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2010 McCready et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Inhibition of extracellular hsp90α inhibits cancer cell motility by preventing plasmin activation. HT-1080 cells were treated with control, IgG, plasmin, anti-hsp90α antibody, or plasmin plus anti-hsp90α antibody. A transwell migration assay was performed and cells that migrated through the chamber were counted. Results are from four independent experiments and expressed as percentage decrease from control (100%). Anti-hsp90α antibody results in a 37% decrease in migration (p < 0.01, two tailed t test).