Table 1.
EMT-associated genes overexpressed in CD44+/CD24- cells compared to CD44-/CD24+ cells.
| Gene Symbol | Gene name | GenBank number | Fold- change |
|---|---|---|---|
| AKT3 | V-AKT murine thymoma oncogene homolog 3 | NM_005465 | 2.0 |
| BDNF | Brain-derived neurotropic factor | NM_001709 | 28.8 |
| CDH2 | Cadherin-2 (N-cadherin) | NM_001792 | 29.8 |
| CTGF | Connective tissue growth factor | NM_001901 | 33.5 |
| DAB2 | Disabled homolog 2 | NM_001343 | 2.4 |
| FGFR1 | Fibroblast growth factor receptor 1 | NM_023105 | 2.6 |
| FYN | FYN oncogene related to SRC, FGR, YES | NM_002037 | 10.1 |
| HMGA2 | High mobility AT-hook 2 | NM_003483 | 24.4 |
| IL8 | Interleukin 8 | NM_000584 | 4.8 |
| ILK | Integrin-linked kinase | NM_004517 | 2.1 |
| ITF2/TCF4 | Transcription factor 4 | NM_003199 | 2.1 |
| JAG1 | Jagged 1 | NM_000214 | 2.6 |
| JAK2 | Janus kinase 2 | NM_004972 | 2.0 |
| MAP4K4 | Mitogen activated protein kinase kinase kinase kinase | NM_017792 | 2.0 |
| MMP-2 | Matrix metalloproteinase 2 | NM_004530 | 14.5 |
| NR2F1/COUP-TF1 | Nuclear receptor subfamily 2, group F, member 1 | NM_005654 | 17.9 |
| Periostin | Periostin, osteoblast specific factor | NM_006475 | 81.7 |
| PIK3R1 | PI3 kinase regulatory subunit (p85) | NM_181523 | 2.7 |
| PRKC alpha | Protein kinase C alpha | NM_002737 | 6.8 |
| S100A4 | S100, calcium binding protein A4 | NM_002961 | 7.0 |
| SMAD3 | SMAD, mother against DPP homolog 3 | NM_005902 | 2.0 |
| SMAD7 | SMAD, mother against DPP homolog 7 | NM_005904 | 3.4 |
| SMURF2 | SMAD-specific E3 ubiquitin ligase 2 | NM_022739 | 2.1 |
| SNAI2/SLUG | SNAIL homolog 2 | NM_003068 | 2.3 |
| SPARC | Secreted protein cysteine-rich (osteonectin) | NM_003118 | 107.7 |
| TGFβ1 | Transforming growth factor beta 1 | NM_011577 | 4.6 |
| TGFβ2 | Transforming growth factor beta 2 | NM_003238 | 3.4 |
| TWIST2 | TWIST homology 2 | NM_057179 | 4.8 |
| Wnt5A | Wingless type, MMTV integration family member, type 5A | NM_003392 | 6.9 |
| Wnt5B | Wingless type, MMTV integration family member, type 5B | NM_030775 | 60.1 |
| ZEB-1/TCF8 | Transcription factor 8 | NM_024285 | 27.8 |
| ZEB-2/ZFHX1B | Zinc finger E-box binding homeobox 2 | NM_014795 | 8.3 |