Figure 1.

Genotypes and minor allele frequencies of five low-risk breast cancer susceptibility alleles or SNPs in human breast cancer cell lines. 1a. Gray bars represent SNP genotype frequencies of 21,860 blood-derived samples from breast cancer cases reported by the breast cancer association consortium BCAC [10], and white bars represent genotype frequencies in 40 breast cancer cell lines. Maj H, major homozygotes; Min H, minor homozygotes; and Het, heterozygote allele carriers. The major and minor alleles of each allele are indicated between brackets. 1b. Black and gray bars represent minor allele frequencies in 22,578 population controls and 21,860 breast cancer cases, respectively, as reported by BCAC [10]. White bars represent frequencies identified in 40 breast cancer cell lines.