Table 4.
Gene | Genotype (Number of cell lines) |
Average expression level (Normalized Ct values) |
---|---|---|
MAP3K1 | Het (n = 14) | 24 ± 2 |
Maj H no loss (n = 4) | 24 ± 4 | |
Min H no loss (n = 2) | 24 ± 0 | |
Maj H allelic loss (n = 1) | 26 | |
Min H allelic loss (n = 6) | 25 ± 1 | |
FGFR2 | Het (n = 7) | 36 ± 5 |
Maj H no loss (n = 4) | 31 ± 7 | |
Min H no loss (n = 1) | 33 | |
Maj H allelic loss (n = 6) | 35 ± 6 | |
Min H allelic loss (n = 6) | 38 ± 6 | |
TNRC9 | Het (n = 14) | 30 ± 8 |
Maj H no loss (n = 2) | 24 ± 2 | |
Min H no loss (n = 3) | 36 ± 8 | |
Maj H allelic loss (n = 1) | 45 | |
Min H allelic loss (n = 7) | 36 ± 9 | |
LSP1 | Het (n = 7) | 37 ± 4 |
Maj H no loss (n = 8) | 37 ± 4 | |
Min H no loss (n = 2) | 41 ± 5 | |
Maj H allelic loss (n = 3) | 40 ± 5 | |
Min H allelic loss (n = 7) | 38 ± 6 |
Although numbers are small for some sample groups, there are no apparent differences in gene expression levels related to allelic loss status. Allelic loss data and qPCR expression data are detailed in Table 1 and Table 3, respectively. Maj H, major homozygotes; Min H, minor homozygotes; Het, heterozygote allele carriers.